Dr. Choupan is an Assistant Professor of Neurology at the Stevens Neuroimaging and Informatics Institute, Department of Neurology at USC, as well as head of the INI Microstructural Imaging Group (IMG). Her focus has been on employing computational neuroimage methods to improve our understanding of brain anatomy and function in normal aging and neurological disorders. In particular, through her multiple, interdisciplinary NIH-funded research projects, she leads research on developing novel neuroimaging techniques that enable detailed profiling of vascular and perivascular features of the brain across lifespan in normal aging, cognitive decline and dementia and other neurodegenerative disorders. Perivascular spaces are a major component of the clearance system and plays an important role in maintaining a healthy functioning brain, particularly in older adults and individuals at risk of neurodegenerative disease. Further, Dr. Choupan’s lab has developed deep learning–based image-level harmonization methods and optimization strategies for large-scale, multi-site/scanner MRI data, specifically designed to enable robust and reproducible study of perivascular spaces. Her goal is to define the role of perivascular spaces in brain health, determine how they are altered across neurological conditions, and identify MRI-based signatures of these changes using advanced neuroimaging techniques. Her work also involves designing 7T MRI imaging sequences that are sensitive to perivascular spaces structure and cerebrospinal fluid dynamics.